{"id":1898,"date":"2025-06-05T10:00:00","date_gmt":"2025-06-05T02:00:00","guid":{"rendered":"https:\/\/citrusflavonoids.com\/?p=1898"},"modified":"2025-06-06T11:59:59","modified_gmt":"2025-06-06T03:59:59","slug":"introduction-to-hesperidin","status":"publish","type":"post","link":"https:\/\/citrusflavonoids.com\/?p=1898","title":{"rendered":"Introduction to Hesperetin"},"content":{"rendered":"\n<p>Hesperidin is a natural flavonoid, the following is a detailed introduction to it:<\/p>\n\n\n\n<p>1. Basic Information<\/p>\n\n\n\n<p>Chinese name: Hesperetin<\/p>\n\n\n\n<p>Alias: 4-Methoxy-3.5&#8242;,7&#8242;-trihydroxyflavanone<\/p>\n\n\n\n<p>English name: Hesperetin<\/p>\n\n\n\n<p>Chemical formula: C16H14O6<\/p>\n\n\n\n<p>Molecular weight: 302.29 (also known as 304.2713)<\/p>\n\n\n\n<p>CAS No.: 520-33-2<\/p>\n\n\n\n<p>EINECS No.: 208-290-2<\/p>\n\n\n\n<p>Appearance: light yellow needle-like crystals or beige to light brown crystalline solid<\/p>\n\n\n\n<p>2. The source and distribution<\/p>\n\n\n\n<p>Hesperidin is mainly derived from the fruits of citrus plants in the family of Rutaceae, such as orange peel, grapefruit peel, lemon peel and so on. It is the glycosyl ligand of hesperidin, which can be metabolized into active hesperidin in the body.<\/p>\n\n\n\n<p>Pharmacological effects<\/p>\n\n\n\n<p>Hesperidin has a wide range of pharmacological effects, including but not limited to:<\/p>\n\n\n\n<p>Antioxidant effect: Hesperidin is a potent antioxidant that can neutralize free radicals in the body, reduce oxidative damage and promote cell health.<\/p>\n\n\n\n<p>Anti-inflammatory effects: Hesperidin can inhibit the mediation of inflammatory mediators, thus indirectly inhibiting the inflammatory response, which is helpful in the prevention of chronic diseases.<\/p>\n\n\n\n<p>Hypolipidemic effect: Hesperidin can inhibit cholesterol-producing enzymes and esterases, thus achieving the role of hypolipidemic.<\/p>\n\n\n\n<p>Cardiovascular protection: Hesperidin has the effect of reducing blood lipids and vascular permeability, which can prevent thrombosis. It can also stimulate certain mitochondrial enzymes such as succinate dehydrogenase to protect the endothelial cell tissue from hypoxia.<\/p>\n\n\n\n<p>Other effects: Hesperidin also has antibacterial, antiviral, antimetabolic, and immune-enhancing effects. In recent years, there are also literature reports that hesperidin and its derivatives have anti-Alzheimer&#8217;s disease, anti-Parkinson&#8217;s disease, anti-hyperglycemia and other effects.<\/p>\n\n\n\n<p>3. Application<\/p>\n\n\n\n<p>Hesperidin is widely used in food, health products, cosmetics and medicine:<\/p>\n\n\n\n<p>Food: used as a food additive, with the role of vitamin P.<\/p>\n\n\n\n<p>Health care products: used in health care drugs and health care products, such as Amway&#8217;s series of products, the U.S. hot health care products vitality 50 and so on.<\/p>\n\n\n\n<p>Cosmetics: Used as an additive in cosmetics, e.g. Clarins&#8217; various night creams contain hesperidin.<\/p>\n\n\n\n<p>Pharmaceuticals: Hesperidin is used as a raw material for medicines, and the main therapeutic effects of related medicines are stomachic, expectorant, cough suppressant, wind repellent, diuretic, antireflux, and gastric pain reliever.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hesperidin is a natural flavonoid, the following is a d [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1898","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/posts\/1898","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1898"}],"version-history":[{"count":2,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/posts\/1898\/revisions"}],"predecessor-version":[{"id":1901,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/posts\/1898\/revisions\/1901"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=\/wp\/v2\/media\/1899"}],"wp:attachment":[{"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1898"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1898"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/citrusflavonoids.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}