Citrus Bioflavonoids are a class of flavonoids extracted from Citrus Bioflavonoids (the dried young fruit of sour orange and its cultivated varieties or sweet orange in the family of Rutaceae), which have a variety of biological activities and medicinal value.

1. Chemical composition

Citrus Bioflavonoids mainly include fat-soluble citrus bioflavonoids, such as Chuan Chenpi pigment (nobiletin), red orange pigment (tangeretin) and sweet orange flavonoid (sinensetin). These components belong to polymethoxyflavonoids (PMFs), which have stronger physiological activities than general flavonoids.

2. Pharmacological effects

Antioxidant and anti-aging: Citrus Bioflavonoids are rich in flavonoids, which can effectively remove free radicals in the body, inhibit enzyme activity, repair damaged cells, and play the role of antioxidant and anti-aging.

Antibacterial and antiviral: Citrus Bioflavonoids can effectively inhibit a variety of viruses and bacteria, protecting the normal cellular functioning of the body.

Anti-inflammatory & Anti-allergic: Citrus Bioflavonoids have anti-inflammatory and anti-allergic effects, which can relieve inflammation and allergic reactions.

Anti-cancer: Citrus Bioflavonoids has the effect of inhibiting cancer cells and can dissolve cancer cells, which is an aid in cancer treatment.

Improvement of digestive problems: Citrus Bioflavonoids can promote small intestinal propulsion, improve gastric ulcers, regulate gastrointestinal peristalsis, help better digestion and absorption of food, and have a significant improvement on symptoms such as functional indigestion and abdominal distension.

Liver protection: Citrus Bioflavonoids has a protective effect on the liver, can reduce the burden on the liver and promote the detoxification function of the liver.

Regulation of metabolism: Citrus Bioflavonoids has a positive effect on the metabolic process of the human body, can help regulate the metabolic balance of the body, and promote the rational use of energy.

3. Clinical application

Treatment of functional dyspepsia: Citrus Bioflavonoids Tablets (e.g. OLANTI®) is a new 1.2 Chinese medicine independently developed by Qingfeng Pharmaceuticals, which is used for the treatment of functional dyspepsia, which is characterized by postprandial satiety, early satiety, epigastric burning sensation, and epigastric pain. Clinical studies have shown that Citrus Bioflavonoids Tablets can significantly improve the symptoms of functional dyspepsia with excellent safety.

Antibacterial, antiviral, anti-inflammatory, anti-allergic: Citrus Bioflavonoids is also used in medicine for antibacterial, antiviral, anti-inflammatory and anti-allergic treatment.

Cardiovascular protection: Citrus Bioflavonoids has the property of dissolving cancer cells and works on blood circulation in patients with coronary artery disease, and can be used as a cardiotonic agent.

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