The generation of Citrus Bioflavonoids derivatives is mainly based on the flavonoid components extracted from Citrus Bioflavonoids, such as naringenin, hesperidin, neohesperidin, etc., which are obtained by chemical modification or biotransformation, etc., and the following is some relevant information:
1. The main components of Citrus Bioflavonoids
Citrus Bioflavonoids mainly contain dihydroflavonoids and flavonoids components, most of which are polymethoxyflavonoids. The dihydroflavonoid components isolated from Hovenia cepa are mainly hesperidin, hesperidin, naringenin, naringenin, neohesperidin, naringenin, naringenin and so on. In addition, it also contains some polymethoxyflavonoid components, such as Chuan Chenpiin (honey orange flavonoid), 5.7.8.4′-tetramethoxyflavonoids and so on.
2. Citrus Bioflavonoids flavonoids derivatives generation and applications
Metal Salt Derivatives: Certain components in Citrus Bioflavonoids can form metal salt derivatives with alkali and metal salts (e.g. sodium carbonate, potassium carbonate, calcium carbonate, etc.). These derivatives may have altered solubility, stability, or biological activity, making them suitable for different application scenarios.
Degradation products: The dihydroflavonoid disaccharide glycosides in Citrus Bioflavonoids (e.g., hesperidin, neohesperidin, etc.) can be degraded to obtain the corresponding dihydroflavonoid monoglycosides and their glycosides through degradation reactions. These degradation products may be superior to the original disaccharide glycosides in some biological activities, and thus have potential applications. For example, hesperidin monoglycoside and hesperidin are degradation products of hesperidin and neohesperidin, respectively, which may have enhanced antioxidant or other biological activities.
Other chemical modifications: In addition to the above two ways, Citrus Bioflavonoids can be structurally modified by other chemical modifications (e.g., acylation, alkylation, glycosylation, etc.) to generate derivatives with different biological activities. These derivatives may have potential applications in drug discovery, functional foods or cosmetics.
3. Biological activities of Citrus Bioflavonoids and their derivatives
Citrus Bioflavonoids and their derivatives have a variety of biological activities, including antioxidant, anti-inflammatory, antibacterial, antiviral, antitumor, and immunity regulation. These biological activities make Citrus Bioflavonoids and their derivatives have a wide range of application prospects in the fields of medicine, health products, functional foods and cosmetics.